The World s Health Care Crisis

Author: Ibis Sánchez-Serrano
Publisher: Elsevier
ISBN: 0123918758
Format: PDF
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At present, human society is facing a health care crisis that is affecting patients worldwide. In the United States, it is generally believed that the major problem is lack of affordable access to health care (i.e. health insurance). This book takes an unprecedented approach to address this issue by proposing that the major problem is not lack of affordable access to health care per se, but lack of access to better, safer, and more affordable medicines. The latter problem is present not only in the United States and the developing world but also in countries with socialized health care systems, such as Europe and the rest of the industrialized world. This book provides a comparative analysis of the health care systems throughout the world and also examines the biotechnology and pharmaceutical industries. Examines the health care structure of the United States, Europe, and the third world, both separately and comparatively Offers primary source insight through in-depth interviews with pharmaceutical and health care industry leaders from around the world Carefully explains, in clear terms, the intricacies of the health care and pharmaceutical system and how these intricacies have led to the current crisis Offers concrete, comprehensive solutions to the health care crisis

Social Aspects of Drug Discovery Development and Commercialization

Author: Odilia Osakwe
Publisher: Academic Press
ISBN: 0128024976
Format: PDF
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Social Aspects of Drug Discovery, Development and Commercialization provides an insightful analysis of the drug discovery and development landscape as it relates to society. This book examines the scientific, legal, philosophical, economic, political, ethical and cultural factors that contribute to drug development. The pharmaceutical industry is under scrutiny to develop safer and more effective drugs in a quicker and more affordable manner. Recent criticism and debates have emphasized varying opinions on the issues concerning the drug discovery and development process. This book provides thoughtful and valuable discussions and analysis of the social challenges and potential opportunities through all stages of the pharmaceutical process, from inception through marketing. With a unique focus on the social factors that increasingly play a role in how drug development is planned, structured, and executed throughout the drug product lifecycle, this is an essential resource for students, professors, and researchers who seek a better understanding of the interface between the pharmaceutical industry, health care systems, and society. Organized in a sequence of interrelated theories and principles that provide the foundation for increased understanding of the relevant social aspects Includes analysis of important new advances, key scientific and strategic issues, and overviews of recent progress in drug development Provides a global perspective with examples from developed areas, such as the US, Japan, Canada and Europe, as well as faster-growing and emerging economies including Brazil, Russia, India, and China Serves as an essential resource for students, professors, and researchers who seek a better understanding of the interface between the pharmaceutical industry, health care systems, and society

Lean Biomanufacturing

Author: Nigel J Smart
Publisher: Elsevier
ISBN: 1908818409
Format: PDF, ePub, Mobi
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With decreasing profit margins, increasing cost pressures, growing regulatory compliance concerns, mounting pressure from generic drugs and increasing anxiety about the future of healthcare reimbursement, pharmaceutical manufacturers are now forced to re-examine and re-assess the way they have been doing things. In order to sustain profitability, these companies are looking to reduce waste (of all kinds), improve efficiency and increase productivity. Many of them are taking a closer look at lean manufacturing as a way to achieve these goals. Lean biomanufacturing re-visits lean principles and then applies them sympathetically - in a highly practical approach - to the specific needs of pharmaceutical processes, which present significantly different challenges to more mainstream manufacturing processes. A major goal of the book is to highlight those problems and issues that appear more specific or unique to biopharmaceutical manufacturing situations and to provide some insights into what challenges are the important ones to solve and what techniques, tools and mechanisms to employ to be successful. Following an introduction to lean biomanufacturing, the book goes on to discuss lean technologies and methods applied in biomanufacturing. Later chapters cover the creation and implementation of the Transition Plan, issues facing the biopharmaceutical industry, creating a lean approach towards biopharmaceutical processes and the contribution of simulation models in developing these processes. The final chapter covers examples of new technology innovations which help facilitate lean biomanufacturing. A focus on the issues associated with the application of lean principles to biomanufacturing Practical examples of factors which can affect biopharmaceutical processes Coverage of key factors which require integration to run an efficient biopharmaceutical process

Stem Cells

Author: Ariff Bongso
Publisher: World Scientific
ISBN: 9814289388
Format: PDF, ePub, Mobi
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Stem cell biology has drawn tremendous interest in recent years as it promises cures for a variety of incurable diseases. This book deals with the basic and clinical aspects of stem cell research and involves work on the full spectrum of stem cells isolated today. It also covers the conversion of stem cell types into a variety of useful tissues which may be used in the future for transplantation therapy. It is thus aimed at undergraduates, postgraduates, scientists, embryologists, doctors, tissue engineers and anyone who wishes to gain some insight into stem cell biology. This book is important as it is comprehensive and covers all aspects of stem cell biology, from basic research to clinical applications. It will have 33 chapters written by renowned stem cell scientists worldwide. It will be up-to-date and all the chapters include self-explanatory figures, color photographs, graphics and tables. It will be easy to read and give the reader a complete understanding and state of the art of the exciting science and its applications.

Evidence based Practice in Nursing Healthcare

Author: Bernadette Mazurek Melnyk
Publisher: Lippincott Williams & Wilkins
ISBN: 1605477788
Format: PDF, Kindle
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Bernadette Mazurek Melnyk and Ellen Fineout-Overholt are creators of the ARCC (Advancing Research and Clinical practice through close Collaboration) Model, an innovative strategy for implementing and sustaining evidence-based practice in healthcare systems. The ARCC Model is cited as an exemplar of education in evidence-based practice in the Board on Health Care Services and the Institute of Medicine's book, Health Professions Education: A Bridge to Quality. "McInyk and Fineout-Overholt's book should be required reading in all graduate programs. Their text has provided a blueprint for the future of nursing practice and a rigorously substantiated and clearly described means for clinicians, educators, and administrators to participate in improving quality of care." Janet D. Allan, PhD, RN, FAAN Dean and Professor University of Maryland School of Nursing "Evidence-based Practice in Nursing & Healthcare: A Guide to Best Practice has been instrumental in developing a culture of evidence-based practice at Barnes-Jewish Hospital. It is fundamental to our curriculum provided to all levels of staff, from new graduate nurses to the highest levels of hospital leadership." Dr. Patricia Potter, RN, PhD, FAAN, Dr. Gail Rea, RN, PhD, CNE, Dr. Karen Balakas, RN, PhD, CNE, Jennifer Williams, MSN, RN, ACNS-BC, Elizabeth Pratt, MSN, RN, ACNS-BC Evidence Equals Excellence group at Barnes-Jewish Hospital and Barnes-Jewish School of Nursing at Goldfarb Evidence-based Practice in Nursing & Healthcare: A Guide to Best Practice is an exemplary text that spans the continuum of nursing evidence to support best practice. Utilizing this text with undergraduate, RN to BSN, and graduate nursing students, it is the ONLY text that demonstrates how to retrieve, read, and analyze evidence whether it is published as an individual study, systematic review, meta-analysis, best practice guideline, or outcomes management report. Students learn how to utilize multiple complex databases and websites as they move through each chapter. And, they experience dissemination of evidence through the development of presentations, publications, posters, and grants. This is truly a remarkable book that embraces evidence as the basis for nursing practice and patient-centered care and safety. Having used this text with more than 1000 students over the past five years, I can honestly say that I have found no other text that facilitates learning and development of clinical judgment that is grounded in valid, reliable, and applicable evidence. This is a keeper! Alice E. Dupler, JD, APRN-BC Clinical Associate Professor Washington State University College of Nursing "I have used the book since I developed the Evidence-based Practice course for our College of Nursing in Fall 2007. It was the first course of its kind at Indiana State University. It has been well received and the preferred course for all nursing graduate students for completion of their final scholarly projects. The text was essential in developing the course and provides the foundation and guidance that the students need to develop their Evidence Based Practice projects...the students love the text!" Susan Eley PhD, RN, FNP-BC Assistant Professor Director FNP Program Indiana State University

Designing Healthcare That Works

Author: Mark Ackerman
Publisher: Academic Press
ISBN: 0128125845
Format: PDF, ePub, Mobi
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Designing Healthcare That Works: A Sociotechnical Approach takes up the pragmatic, messy problems of designing and implementing sociotechnical solutions which integrate organizational and technical systems for the benefit of human health. The book helps practitioners apply principles of sociotechnical design in healthcare and consider the adoption of new theories of change. As practitioners need new processes and tools to create a more systematic alignment between technical mechanisms and social structures in healthcare, the book helps readers recognize the requirements of this alignment. The systematic understanding developed within the book’s case studies includes new ways of designing and adopting sociotechnical systems in healthcare. For example, helping practitioners examine the role of exogenous factors, like CMS Systems in the U.S. Or, more globally, helping practitioners consider systems external to the boundaries drawn around a particular healthcare IT system is one key to understand the design challenge. Written by scholars in the realm of sociotechnical systems research, the book is a valuable source for medical informatics professionals, software designers and any healthcare providers who are interested in making changes in the design of the systems. Encompasses case studies focusing on specific projects and covering an entire lifecycle of sociotechnical design in healthcare Provides an in-depth view from established scholars in the realm of sociotechnical systems research and related domains Brings a systematic understanding that includes ways of designing and adopting sociotechnical systems in healthcare

Drug Discovery

Author: Tamas Bartfai
Publisher: Academic Press
ISBN: 0080919235
Format: PDF, ePub, Docs
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Everyone expects something from the drug industry. Physicians and patients, investors, regulators and administrators all have an active interest. Everyone wants to know what makes drugs ‘work’ medically and economically. Why are drugs so expensive? Is it the drug companies or investors who demand high profits? What governs the pharmacoeconomics? Why are so few diseases treatable? This book opens the windows and doors of the industry telling the story of drug development by using real stories from inside the process. * Co-written by Graham Lees and Tamas Bartfai who has been involved in the development of drugs taken by more that 20 million people every day * Opens the windows and doors of the most regulated industry in the world, the pharmaceutical industry * Tells the story of drug development by using real examples based on current research and events * Provides an objective, lucid account of the successes and failures, shortcomings and constraints of the pharmaceutical and biotech industries * Gives insights into the development of new drugs to combat multiple conditions including cancer and pain * Balanced, unbiased account of how better to translate basic science into drug discovery

A Practical Guide for Medical Teachers

Author: John Dent
Publisher: Elsevier Health Sciences
ISBN: 0702068934
Format: PDF, ePub, Docs
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The Fifth Edition of the highly praised Practical Guide for Medical Teachers provides a bridge between the theoretical aspects of medical education and the delivery of enthusiastic and effective teaching in basic science and clinical medicine. Healthcare professionals are committed teachers and this book is an essential guide to help them maximise their performance. This highly regarded book recognises the importance of educational skills in the delivery of quality teaching in medicine. The contents offer valuable insights into all important aspects of medical education today. A leading educationalist from the USA joins the book’s editorial team. The continual emergence of new topics is recognised in this new edition with nine new chapters: The role of patients as teachers and assessors; Medical humanities; Decision-making; Alternative medicine; Global awareness; Education at a time of ubiquitous information; Programmative assessment; Student engagement; and Social accountability. An enlarged group of authors from more than 15 countries provides both an international perspective and a multi-professional approach to topics of interest to all healthcare teachers.

Emerging Epidemics

Author: Prakash S. Bisen
Publisher: John Wiley & Sons
ISBN: 1118393252
Format: PDF, ePub
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A global perspective on the management and prevention of emerging and re-emerging diseases Emerging infectious diseases are newly identified or otherwise previously unknown infections that cause public health challenges. Re-emerging infectious diseases are due to both the reappearance of and an increase in the number of infections from a disease that is known, but which had formerly caused so few infections that it was no longer considered a public health problem. The factors that cause the emergence or re-emergence of a disease are diverse. This book takes a look at the world's emerging and re-emerging diseases. It covers the diagnosis, therapy, prevention, and control of a variety of individual diseases, and examines the social and behavioral issues that could contribute to epidemics. Each chapter focuses on an individual disease and provides scientific background and social history as well as the current basics of infection, epidemiology, and control. Emerging Epidemics: Management and Control offers five topics of coverage: FUNDAMENTALS Epidemics fundamentals Disasters and epidemics Biosafety RE-EMERGING EPIDEMICS Tuberculosis Plague NEWLY EMERGING EPIDEMICS Leptospirosis Dengue Japanese Encephalitis Chikungunya Fever West Nile Virus Chandipura Virus Encephalitis Kyasanur Forest Disease Hantavirus Human, Avian, and Swine Influenza Severe Acute Respiratory Syndrome Nipah Virus Paragonimiasis Melioidosis POTENTIAL EPIDEMICS Biowarfare and bioterrorism Food contamination and food terrorism Antimicrobial resistance VECTOR CONTROL METHODS Mosquito control Other disease vectors and their control Offering an integrated, worldwide overview of the complexity of the epidemiology of infections, Emerging Epidemics will be a valuable resource for students, physicians, and scientists working in veterinary, medical, and the pharmaceutical sciences.