Immunological and Molecular Aspects of Bacterial Virulence

Author: S. Patrick
Publisher: Wiley-Blackwell
ISBN: 9780471952510
Format: PDF
Download Now
The living mammalian host provides a unique environment for bacterial colonisation. It is not only subject to passive change but has evolved highly specialised mechanisms, together constituting the immune system, to actively discourage microbial colonisation. It brings together under one cover aspects of the human immune response to bacteria and the genetic systems of pathogenic bacteria as well as details of the bacterial molecules involved in virulence. Although biased towards pathogenic bacteria of humans, the principles covered are equally applicable to veterinary pathogens. Immunological and Molecular Aspects of Bacterial Virulence caters for undergraduate and postgraduate science students of human and veterinary bacteriology who wish to gain a better understanding of the fundamental aspects of bacterial virulence.

Textbook of Immunology

Author: SK Mohanty
Publisher: JP Medical Ltd
ISBN: 9350904748
Format: PDF, Kindle
Download Now
This new edition has been fully revised to provide the most up to date information in the field of immunology. Beginning with a brief history of the subject, the following chapters cover all aspects of immunology, from basic immunity and antigens, to immunodeficiency disorders including HIV, tumour immunology, and transplantation immunology. This concise second edition is highly illustrated with detailed graphics, colour diagrams, charts and tables, and each chapter features study questions and suggestions for further reading. Key points Fully revised, second edition, providing latest information on complete field of immunology Highly illustrated with graphics, diagrams, charts and tables Study questions and further reading suggestions included in each chapter Previous edition published in 2007

Principles and Practice of Clinical Bacteriology

Author: Stephen Gillespie
Publisher: John Wiley & Sons
ISBN: 0470035323
Format: PDF, ePub, Mobi
Download Now
Since the publication of the last edition of Principles and Practice of Clinical Bacteriology, our understanding of bacterial genetics and pathogenicity has been transformed due to the availability of whole genome sequences and new technologies such as proteomics and transcriptomics. The present, completely revised second edition of this greatly valued work has been developed to integrate this new knowledge in a clinically relevant manner. Principles and Practice of Clinical Bacteriology, Second Edition, provides the reader with invaluable information on the parasitology, pathogenesis, epidemiology and treatment strategies for each pathogen while offering a succinct outline of the best current methods for diagnosis of human bacterial diseases. With contributions from an international team of experts in the field, this book is an invaluable reference work for all clinical microbiologists, infectious disease physicians, public health physicians and trainees within these disciplines.

Salmonella Infections

Author: Pietro Mastroeni
Publisher: Cambridge University Press
ISBN: 9780521835046
Format: PDF, ePub
Download Now
Salmonella enterica encompasses a diverse range of bacteria that cause a spectrum of diseases in many hosts. Advancements in prevention and treatment of S. enterica infections have at times been hampered by compartmentalization of research efforts and lack of multidisciplinary approaches. This book attempts to cover a diverse range of topics related to the biology of S. enterica infections, including epidemiological and clinical aspects, molecular pathogenesis, immunity to disease and vaccines. S. enterica infections are important zoonoses and therefore material on infections of animals and public health issues have also been considered. Each chapter can be read independently, but the full contents of the book will provide the reader with up-to-date knowledge on all the key aspects of salmonellosis in humans and animals. It will therefore be of interest to graduate students and researchers, as well as to clinicians, whose research focuses on this important pathogen.

Immune Recognition and Evasion Molecular Aspects of Host Parasite Interaction

Author: L.H.T. Van Der Ploeg
Publisher: Elsevier
ISBN: 0323155669
Format: PDF, Docs
Download Now
Immune Recognition and Evasion: Molecular Aspects of Host-Parasite Interaction reviews recent advances in understanding the genetic basis of host-parasite interactions, with emphasis on antigenic epitopes, the genetics of parasites, the molecular mechanisms of immune recognition and evasion, and the way that cytokines and hormones act on host-parasite interactions. Organized into four parts encompassing 25 chapters, this volume begins with an overview of the genomic organization of the T cell receptor genes and the contribution of non-B DNA structures to switch recombination in immunoglobulin genes. It then discusses signal transduction by class II molecules encoded by the major histocompatibility complex la and the biological consequences of this process; allelic polymorphism of HLA class II antigens and its connection to the molecular basis of autoimmunity; mimicry between HLAB27 and bacteria; and genetic control of susceptibility to helminth infection. The reader is also introduced to recognition of protein antigens by antibodies; recognition of influenza antigens by class I-restricted cytotoxic T lymphocytes; the biochemical basis of cachexia of infection; mechanisms of antigenic variation in Plasmodium; and rational design of trypanocidal drugs. Geneticists and molecular biologists will gain valuable information from this book.

Bacterial Pathogenesis

Author: Virginia L. Clark
Publisher: Gulf Professional Publishing
ISBN: 9780121821371
Format: PDF
Download Now
This volume of Methods in Enzymology contains contributions covering the wide spectrum of interactions between bacterial pathogens and their eukaryotic hosts. It complements Volume 235, in which methods for the isolation and identification of bacterial pathogens and associated virulence determinants are described. Since the study of bacterial pathogenesis borrows from a great variety of technologies and disciplines, we aim to provide the reader with a representative sample of the most advanced pathogenesis research.

Immunological Aspects of Gastroenterology

Author: Y.R. Mahida
Publisher: Springer Science & Business Media
ISBN: 940100790X
Format: PDF, ePub
Download Now
Diseases of the gastrointestinal tract are common. There is increasing appreciation of the importance of the immune system in the pathogenesis of a number of these diseases. This book covers basic aspects of innate and adaptive immunity in the gastrointestinal tract, oral tolerance, and cellular and molecular mechanisms of acute and chronic inflammation. Specific disease covered include bacterial infections, human immunodeficiency virus (HIV) infection, coeliac disease, and inflammatory bowel disease. Other topics include mucosal immunisation and intestinal transplantation immunology. The readership of this book includes clinicians, scientists, and students interested in the gastrointestinal tract.

Anthrax History Biology Global Distribution Clinical Aspects Immunology and Molecular Biology

Author: Robert E. Levin
Publisher: Bentham Science Publishers
ISBN: 1608058867
Format: PDF, ePub
Download Now
Following the post 9/11 distribution of anthrax spores through the U.S. mail, and the resulting deaths of five individuals - primarily due to initial misdiagnosis - there has been a renewed interest in anthrax among clinicians and intelligence agencies, particularly as a biological warfare agent. This monograph brings forth essential knowledge about anthrax. Included in this volume, are, the early history, non-natural outbreaks of anthrax, characteristics of the causative organism Bacillus anthracis and its relationship to other members of the B. cereus family. Also included are reports on extensive clinical findings, mechanisms of anthrax virulence and the genetics responsible for these virulence factors. The extensive studies over the years regarding the development of veterinary and human vaccines, and molecular studies, including conventional PCR and real-time PCR are explained in comprehensive detail, with the help of tables, figures and extensive references. This eBook serves as an advanced presentation and reference work for individuals seeking detailed information regarding anthrax and as a primary guide for individuals pursuing studies on anthrax.

Molecular Medical Microbiology

Author: Yi-Wei Tang
Publisher: Academic Press
ISBN: 0123977630
Format: PDF, ePub, Mobi
Download Now
The molecular age has brought about dramatic changes in medical microbiology, and great leaps in our understanding of the mechanisms of infectious disease. Molecular Medical Microbiology is the first book to synthesise the many new developments in both molecular and clinical research in a single comprehensive resource. This timely and authoritative three-volume work is an invaluable reference source of medical bacteriology. Comprising more than 100 chapters, organized into 17 major sections, the scope of this impressive work is wide-ranging. Written by experts in the field, chapters include cutting-edge information, and clinical overviews for each major bacterial group, in addition to the latest updates on vaccine development, molecular technology and diagnostic technology. Topics covered include bacterial structure, cell function, and genetics; mechanisms of pathogenesis and prevention; antibacterial agents; and infections ranging from gastrointestinal to urinary tract, centrtal nervous system, respiratory tract, and more. The first comprehensive and accessible reference on molecular medical microbiology Full color presentation througout In-depth discussion of individual pathogenic bacteria in a system-oriented approach Includes a clinical overview for each major bacterial group Presents the latest information on vaccine development, molecular technology, and diagnostic technology More than 100 chapters covering all major groups of bacteria Written by an international panel of authors who are experts in their respective disciplines