Accurate Results in the Clinical Laboratory

Author: Amitava Dasgupta
Publisher: Newnes
ISBN: 0124158587
Format: PDF
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This practical, easy-to-use guide, named to Doody’s Core Titles 2013, addresses interference issues in all laboratory tests, including patient epigenetics, process of specimen collection, enzymes, biomarkers. Clinicians and laboratory scientists can therefore rely on one reference which speaks to both their needs of accurate specimen analysis and optimal patient care. Erroneous hospital and pathology laboratory results can be confusing and problematic, especially in acute care situations. While some factors creating interference, can be identified in the laboratory, detecting many others is often dependent on clinical details unavailable to the laboratory scientists or pathologists. Therefore, clinicians must become proficient in identifying such erroneous reports, and working with pathologists and laboratory scientists so that they can understand the source of such interferences, correct the results, and then decide what course of action must be followed for proper patient management. Named to Doody’s Core Titles 2013, a collection development tool for health sciences libraries of all sizes, by Doody Enterprises Practical information for both clinicians and laboratory scientists, presented in the form of tables and charts for easy reference Focus on range and sources of interferences rather than details of toxicologic mechanisms which are well covered in toxicology textbooks Covers interferences across endocrine, oncology, hematology, immunohistochemistry, immunology, serology, microbiology, and molecular testing

Endocrine Biomarkers

Author: Hossein Sadrzadeh
Publisher: Elsevier
ISBN: 0128034181
Format: PDF, ePub, Mobi
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Endocrine Biomarkers: Clinical Aspects and Laboratory Determination covers all the pre-analytical variables that can affect test results, both in the clinic and laboratory. Biomarkers of endocrine and bone diseases are discussed from both clinical and laboratory perspectives, and the authors elaborate on the teamwork-based app+roach between the clinician and the laboratory professional in the diagnosis and management of endocrine and bone disorders. Discussions include test utilization, laboratory measurement methods, harmonization and standardization, interpretation of results, and reference intervals. Each chapter ends with a discussion of one or two relevant cases with shared opinions from both a clinician and a clinical chemist. Each chapter also includes a summary box outlining key points and common pitfalls in the use of specific disease biomarkers and tests. Focuses on the traditional, current, and emerging clinical chemistry tests for endocrine and bone diseases, along with their application in individual clinical management Presents a brief discussion of each disorder and its respective interrelationships, along with laboratory methodologies that can be used to aid in evaluation of disorders Reviews common approaches to the measurement of the relevant hormones, with a special focus on measures that require a structured clinical testing scenario Reviews novel chemistry tests as potential means of future diagnostic tests Provides an overview of the current methodology and controversies in the concept of target lipid levels, paying particular attention to the role of clinical chemistry in helping to implement population health targets

Clinical Diagnostic Tests

Author: Michael Laposata
Publisher: Springer Publishing Company
ISBN: 1620700832
Format: PDF
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" Clinical Diagnostic Tests is a convenient, quick-reference guide to common errors and pitfalls in test selection and result interpretation for practitioners and trainees in all areas of clinical medicine. Authored by recognized experts and educators in laboratory medicine, it provides timely, practical guidance about what to doóand what not to doófor practitioners ordering or interpreting clinical tests. Each topic features a concise overview and summary followed by a list of bulleted ìstandards of careî that will enable practitioners to quickly recognize and avert a potential problem. Organized for easy access to critical information, this pithy guide addresses all major issues practitioners are likely to encounter during their day-to-day clinical work. It is intended for practitioners in pathology, laboratory medicine, primary care as well as nurse practitioners and physician assistants. It is also a valuable resource for clinical trainees and students who need to learn effective, efficient use of the clinical lab in practice. Key Features: Provides practical guidance for avoiding common errors and pitfalls in lab test selection and interpretation Includes pithy overviews and recommendations for quick reference Written by expert authors and educators in laboratory medicine Presents bulleted ìstandards of careî Serves as a concise, to-the-point teaching guide About the Author: Michael Laposata, MD, PhD , is Chair of Pathology, Director of Division of Laboratory Medicine and Clinical Laboratories, University of Texas Medical Branch, Galveston "

Clinical Chemistry Immunology and Laboratory Quality Control

Author: Amitava Dasgupta
Publisher: Academic Press
ISBN: 0124079350
Format: PDF, Mobi
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All pathology residents must have a good command of clinical chemistry, toxicology, immunology, and laboratory statistics to be successful pathologists, as well as to pass the American Board of Pathology examination. Clinical chemistry, however, is a topic in which many senior medical students and pathology residents face challenges. Clinical Chemistry, Immunology and Laboratory Quality Control meets this challenge head on with a clear and easy-to-read presentation of core topics and detailed case studies that illustrate the application of clinical chemistry knowledge to everyday patient care. This basic primer offers practical examples of how things function in the pathology clinic as well as useful lists, sample questions, and a bullet-point format ideal for quick pre-Board review. While larger textbooks in clinical chemistry provide highly detailed information regarding instrumentation and statistics, this may be too much information for students, residents, and clinicians. This book is designed to educate senior medical students, residents, and fellows, and to "refresh" the knowledge base of practicing clinicians on how tests are performed in their laboratories (i.e., method principles, interferences, and limitations). Takes a practical and easy-to-read approach to understanding clinical chemistry and toxicology Covers all important clinical information found in larger textbooks in a more succinct and easy-to-understand manner Covers essential concepts in instrumentation and statistics in such a way that fellows and clinicians understand the methods without having to become specialists in the field Includes chapters on drug-herb interaction and pharmacogenomics, topics not covered by textbooks in the field of clinical chemistry or laboratory medicine

District Laboratory Practice in Tropical Countries

Author: Monica Cheesbrough
Publisher: Cambridge University Press
ISBN: 9780521676311
Format: PDF
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A practical and well-illustrated guide to microbiological, haematological, and blood transfusion techniques. The microbiology chapter focuses on common tropical infections. The haematology chapter deals with the investigation of anaemia and haemoglobinopathies. The blood transfusion chapter provides guidelines on the use of blood and blood substitutes, selection of donors and collection.

Introduction to the Clinical Laboratory

Author: Robert Preston MacFate
Publisher:
ISBN:
Format: PDF
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General laboratory rules. Specimens for clinical laboratory examination. Examination of Urine. Blood Chemistry. Examination of stomach contents. Examination of feces. Hematologic procedures. Serologic procedures. Examination of cerebrospinal fluid. Microbiologic procedures. Parasitologic procedures. Physical procedures. Chemical procedures. Supplies. Glassware. Statistical methods in the clinical laboratory. Animals used in the clinical laboratory. Health, safety, and first aid in the laboratory. Conversion factors. Atomic weights table. Required equipment.

Registries for Evaluating Patient Outcomes

Author: Agency for Healthcare Research and Quality/AHRQ
Publisher: Government Printing Office
ISBN: 1587634333
Format: PDF, ePub, Mobi
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This User’s Guide is intended to support the design, implementation, analysis, interpretation, and quality evaluation of registries created to increase understanding of patient outcomes. For the purposes of this guide, a patient registry is an organized system that uses observational study methods to collect uniform data (clinical and other) to evaluate specified outcomes for a population defined by a particular disease, condition, or exposure, and that serves one or more predetermined scientific, clinical, or policy purposes. A registry database is a file (or files) derived from the registry. Although registries can serve many purposes, this guide focuses on registries created for one or more of the following purposes: to describe the natural history of disease, to determine clinical effectiveness or cost-effectiveness of health care products and services, to measure or monitor safety and harm, and/or to measure quality of care. Registries are classified according to how their populations are defined. For example, product registries include patients who have been exposed to biopharmaceutical products or medical devices. Health services registries consist of patients who have had a common procedure, clinical encounter, or hospitalization. Disease or condition registries are defined by patients having the same diagnosis, such as cystic fibrosis or heart failure. The User’s Guide was created by researchers affiliated with AHRQ’s Effective Health Care Program, particularly those who participated in AHRQ’s DEcIDE (Developing Evidence to Inform Decisions About Effectiveness) program. Chapters were subject to multiple internal and external independent reviews.

Quality in Laboratory Hemostasis and Thrombosis

Author: Steve Kitchen
Publisher: John Wiley & Sons
ISBN: 1118543491
Format: PDF
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The hemostasis laboratory has a vital role in the diagnosis and management of patients with familial and acquired haemorrhagic and thrombotic disorders. Its role in the monitoring of traditional anticoagulant therapy, as well as therapy using new anticoagulants, presents new challenges to the laboratory. This new edition addresses these important issues, as well as international guidelines for testing, the development of international standard materials, management of haemostasis testing from the laboratory to the point-of-care, and molecular genetic testing.